| AIDS Cases | Total Population | AIDS Rate per 100,000 | |
| Zip Code | |||
| 10001/Chelsea-Clinton | 1087 | 17,310 | 6,279.61 |
| 10002/Union Square-Lower East Side | 1791 | 84,870 | 2,110.29 |
| 10003/Union Square-Lower East Side | 2016 | 53,673 | 3,756.08 |
| 10004/Lower Manhattan | 53 | 1,225 | 4,326.53 |
| 10005/Lower Manhattan | 30 | 884 | 3,393.67 |
| 10006/Lower Manhattan | 49 | 1,447 | 3,386.32 |
| 10007/Lower Manhattan | 109 | 3,522 | 3,094.83 |
| 10009/Union Square-Lower East Side | 2026 | 58,595 | 3,457.63 |
| 10010/Gramercy Park-Murray Hill | 868 | 26,408 | 3,286.88 |
| 10011/Chelsea-Clinton | 3646 | 46,669 | 7,812.47 |
| 10012/Greenwich Village-Soho | 670 | 26,000 | 2,576.92 |
| 10013/Greenwich Village-Soho | 812 | 25,042 | 3,242.55 |
| 10014/Greenwich Village-Soho | 2134 | 32,667 | 6,532.59 |
| 10016/Gramercy Park-Murray Hill | 1814 | 51,217 | 3,541.79 |
| 10017/Gramercy Park-Murray Hill | 265 | 16,201 | 1,635.70 |
| 10018/Chelsea-Clinton | 339 | 4,255 | 7,967.10 |
| 10019/Chelsea-Clinton | 1452 | 36,012 | 4,031.99 |
| 10021/Upper East Side | 1138 | 102,078 | 1,114.83 |
| 10022/Gramercy Park-Murray Hill | 576 | 30,642 | 1,879.77 |
| 10023/Upper West Side | 1390 | 62,206 | 2,234.51 |
| 10024/Upper West Side | 1612 | 61,414 | 2,624.81 |
| 10025/Upper West Side | 3471 | 97,086 | 3,575.18 |
| 10026/Central Harlem-Morningside Heights | 1559 | 30,377 | 5,132.17 |
| 10027/Central Harlem-Morningside Heights | 2094 | 56,168 | 3,728.10 |
| 10028/Upper East Side | 635 | 44,987 | 1,411.52 |
| 10029/East Harlem | 3082 | 75,390 | 4,088.08 |
| 10030/Central Harlem-Morningside Heights | 1321 | 25,847 | 5,110.84 |
| 10031/Washington Heights-Inwood | 1642 | 60,221 | 2,726.62 |
| 10032/Washington Heights-Inwood | 1452 | 63,842 | 2,274.36 |
| 10033/Washington Heights-Inwood | 675 | 58,259 | 1,158.62 |
| 10034/Washington Heights-Inwood | 551 | 41,756 | 1,319.57 |
| 10035/East Harlem | 1745 | 32,702 | 5,336.07 |
| 10036/Chelsea-Clinton | 1324 | 18,751 | 7,060.96 |
| 10037/Central Harlem-Morningside Heights | 767 | 16,984 | 4,516.02 |
| 10038/Lower Manhattan | 255 | 15,574 | 1,637.34 |
| 10039/Central Harlem-Morningside Heights | 810 | 21,737 | 3,726.37 |
| 10040/Washington Heights-Inwood | 459 | 46,599 | 985.00 |
| 10044/Upper East Side | 114 | 9,520 | 1,197.48 |
| 10128/Upper East Side | 395 | 59,856 | 659.92 |
| 10280/Lower Manhattan | 44 | 6,614 | 665.26 |
| Manhattan | 49,695 | 1,537,195 | 665.26 |
| New York State | 169,556 | 18,976,457 | 893.51 |
| United States | 956,019 | 281,421,906 | 339.71 |